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Chemical Sterilization – Victoria Stilwell & Her Vet Weigh In

By: Scott H
Scott Haiduc is the Director of Publishing for iHeartDogs, iHeartCats and The Hero Company. When not working, Scott spends his time on the farm, taking care of his animals and crops.Read more
| April 12, 2014

Zeuterin™ is the first ever FDA approved injectable sterilization in the U.S. However, it is not new to the market. It was actually introduced in 2003 under a different name, and then pulled in 2004 with Ark Sciences claiming they were having “supply problems.”

It is now back and people are eager to jump on the bandwagon without asking too many questions. But is the drug really a better option? What exactly does it do? How will your dog react?

How Zeutrin Works.

According to the Ark Sciences website, “after injection, the compound diffuses in all directions from the center of the testis. Zinc, in the specific concentration used, is a spermicide and proven to destroy spermatozoa in all stages of maturation in the seminiferous tubules, rete testis and epididymides. The result is permanent and irreversible fibrosis in the testicle rendering the dog sterile.”

Even though it's not surgery, your dog will still be sedated and have a recovery period after Zeutrin
Even though it’s not surgery, your dog will still be sedated and have a recovery period after Zeutrin

While many of us probably envision a quick, vaccine-like injection and then home with our now-sterile dog, this is not the case. The procedure is actually quite in depth and tricky, which veterinarians must be trained on. Your dog will be given one injection into each testicle, which has to be placed at just the right location and then done slowly – over 5-12seconds per injection. The amount of drug used must also be calculated accurately and your dog needs to be sedated as it is uncomfortable. In addition, because your dog will still look intact, he will be tattooed with a small green “Z” for identification purposes. He will also retain about 50% of his testosterone.

Post procedure recovery includes pain, discomfort (some dogs vomit due to pain), and swollen testicles. Your dog will need pain medicine in order to stay comfortable and activity will need to be limited just like with a traditional neuter.

Is It Better Than Traditional Neutering?

Health

Victoria Stilwell, celebrity dog trainer and host of Animal Planet’s “It’s Me or The Dog,” and her vet, Dr. Duffy Jones  weigh in about the pros and cons to the drug. Stilwell is busy working on some new projects, including a new large-scale show with a major network that celebrates the human-animal bond, she was kind enough to spare a few minutes to talk with us about the pros and cons of Zeutrin.

No one is sure about long-term effects because it hasn’t been around long enough for us to know. Tests and trials in the labs can only go so far. In addition, it is important to note that chemical sterilization will not prevent against prostrate or testicular cancer the way neutering does.

And, while there are risks to the traditional method, as least we know what those are and we also know that almost every dog lives a fully, healthy life after being neutered.

But, on the other side of the coin, “removing your pet’s ovaries or testes removes these hormones and can result in increased risk of health problems such as incontinence and some types of cancer. ” (https://www.avma.org) Along with weight gain, these risks maybe lessened with chemical sterilization, which leaves half of the testosterone in place.

 

“Neutering controls overpopulation, which is what we want,” Stilwell contines. “So Zuetrin does give an option to those who do not want to neuter because it ruins the ‘appearance’ of the dog.” With the new drug, the dog will still look “entire.”

Dr. Jones, owner and practicing veterinarian of Peachtree Hills Animal Hospital in Atlanta, Ga. also worries about long term effects, such as tumors at the injection site and ulcers from improperly placed injections, something that happened back in 2003.

Behavior

Aside from health, there are also behavioral concerns.

“I have concerns about the reduction of testosterone in dogs.” Dr. Jones says.  “A surgical neuter reduces the testosterone down to zero, while Zeuterin reduces it to about half the level of an intact dog. Having testosterone could cause these dogs to be more aggressive. More aggressive dogs could lead to more dog fights, and also human bites.”

If this drug becomes widespread in the rescue world, Dr. Jones worries about the aggressive side-effects having a negative effect on adoptions.

“An unintended consequence might people will become reluctant to adopt these dogs for fear of having a family member or child be bitten.” Dr. Jones explains. “This will lead to more dogs being euthanized in shelters.”

“It’s relatively new so it’s too early to know what behavioral side effects, if any, it will have,” Stilwell adds. “In general, and this is a generalization, intact males with testosterone can have a higher reactivity level than dogs that have been neutered. So will the presences of testosterone, even if it’s half, mean these dogs will be more reactive? We don’t know yet so there is that risk.”

She notes that even traditional neutering does not always remove aggression, and can actually make it worse in some cases.

The Bottom Line

Stilwell adds that the biggest problem is that you can have one study saying spaying or neutering is good and solves behavior and health issues, and another that says it’s bad. That’s because you are dealing with individual dogs which are affected differently by the procedure.

Their resulting advice? Talk to your veterinarian and dog trainer about what is best for your individual dog. Weigh the risks, the pros and cons, to your individual dog before making a choice.

About the Author

Based in Tustin, Calif., animal lover Kristina N. Lotz is a Certified Professional Dog Trainer – Knowledge Assessed (CPDT-KA) and works as a full time trainer. She also owns her own custom pet products company, A Fairytail House, where she makes personalized collars, leashes, beds, keepsake pillows and blankets, and anything else your imagine can think up. In her spare time, she trains and competes in herding, agility, obedience, rally, and conformation with her Shetland Sheepdogs.

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